Department of Neurology - Faculty

Bruce M. Coull, MD
Professor of Neurology
Professor of Medicine
Associate Dean for Clinical Affairs, COM
Chief Medical Officer, UPH Practices
William M. Feinberg MD Endowed Chair in Stroke Research

Education/Training:

BS: University of Pittsburgh, 1966

MS: University of Pittsburgh, 1968

MD: University of Pittsburgh, 1972

Internship: Presbyterian University Hospital, 1972-73

Residency: Stanford University, 1973-76

Fellowship (Developmental Neurology): Stanford University, 1976-78

Board Certification:

Neurology, American Board of Psychiatry and Neurology

Vascular Neurology, American Board of Psychiatry and Neurology, 2005

Clinical/Research Interests: Cerebrovascular Disease; Lupus Anticoagulant

Publications:

Articles:

• Retzloff DG, Coull BM, Coull J. A microchemical study of gas-phase kinetics for three irreversible reactions. Journal of Physical Chemistry 74:2455-59, 1970.
• Chorbajian T, Coull BM, Coull J. An in numero study of glucose-insulin interaction. Bulletin of Mathematics and Biophysics 33:451-62, 1971.
• Coull BM, Pedley TA. Intermittent photic stimulation: Clinical usefulness of non-convulsive responses. Electroencephalography and Clinical Neurophysiology 44:353-363, 1978.
• Coull BM, Cutler RWP. Light-evoked release of endogenous glycine into the perfused vitreous of the intact rat eye. Investigative Ophthalmology and Visual Science 17:682-684, 1978
• Coull BM, Owens DK and Cutler RWP. The release of endogenous amino acids into the vitreous of the intact eye of the albino rat: Effect of light, potassium and ouabain. Brain Research 210:301-309, 1981.
• Rosenberg NL, Coull BM. Myelopathy after scorpion sting. Archives of Neurology 39:127, 1982.
• Porter JM, Rivers SP, Coull BM, Baur GM. Thoracic outlet syndrome: A conservative approach. Vascular Diagnosis and Therapy 3:35-39, 1982.
• Woodward WR, Coull BM. Studies of effect of kainic acid lesions in the dorsal lateral geniculate nucleus of rat. Journal of Comparative Neurology 211:93-103, 1982.
• Hart RG, Coull BM and Hart. Early recurrent embolism associated with nonvalvular atrial fibrillation: A retrospective study. Stroke 14;688-693, 1983.
• Hakim AM, Furlan AJ, Hart RG, Coull BM and the Cerebral Embolism Study Group. Immediate anticoagulation of embolic stroke: A randomized trial. Stroke 14:668-676, 1983.
• The American-Canadian Cooperative Study Group. Progress Report: Persantine aspirin trial in cerebral ischemia. Stroke 14:99-103, 1983.
• Woodward WR and Coull BM. Localization and organization of geniculocortical and corticofugal fiber tracts within the subcortical white matter. Neuroscience 12:1089-1099, 1984.
• Miller VT, Coull BM, Yatsu FM, Shah AB, Beamer NB. Prostacyclin infusion in acute cerebral infarction. Neurology 34:1431-1436, 1984.
• Hakim AM, Furlan AJ, Hart RG, Coull BM, and the Cerebral Embolism Study Group. Immediate anticoagulation of embolic stroke: Brain hemorrhage and management options. Stroke 15:779-789, 1984.
• Hart RG, Miller VT, Coull BM, Bril V. Cerebral infarction associated with lupus anticoagulants - preliminary report. Stroke 15:114-118, 1984.
• The American-Canadian Cooperative Study Group. Persantine aspirin trial in cerebral ischemia, Part II: Endpoint results. Stroke 16:406-415, 1985.
• Hakim AM, Furlan AJ, Hart RG, Coull BM, and the Cerebral Embolism Study Group. Cardioembolic stroke, early anticoagulation, and brain hemorrhage. Archives of Internal Medicine 147:630-640, 1987.
• Shah AB, Beamer NB, Coull BM. Enhanced in vivo platelet activation in subtypes of ischemic strokes. Stroke 16:643-647, 1985.
• Gumerlock MK, Coull BM, Howieson J, Buchan C, Neuwelt EA. Late stenosis of a superficial temporal-middle cerebral artery bypass: Angiographic and histological findings. Neurosurgery 16:650-657, 1985.
• Yatsu FM, Becker C, McLeroy KR, Coull BM, Feibel J, Howard G, Toole JF, Walker MD. Community Hospital-Based Stroke Programs: North Carolina, Oregon, and New York. I. Goals, objectives and methodology. Stroke 17:276-284, 1986.
• Becker C, Howard G, McLeroy KR, Yatsu FM, Toole JF, Coull BM, Feibel J, Walker MD. Community Hospital-Based Stroke Programs: North Carolina, Oregon, and New York. II. Description of study population. Stroke 17:285-293, 1986.
• Howard G, Walker MD, Becker C, Coull BM, Feibel J, McLeroy K, Toole JF, Yatsu F. Community Hospital-Based Stroke Programs: North Carolina, Oregon, and New York. III. Factors influencing survival after stroke: Proportional hazards analysis of 4219 patients. Stroke 17:294-299, 1986.
• Linz DH, de Garmo PL, Morton WE, Wiens AN, Coull BM and Maricle RA. Organic solvent-induced encephalopathy in industrial painters. Journal of Occupational Medicine 28:119-125, 1986.
• Coull BM, Beamer NB, Seaman GVF. Physicochemical risk factors in stroke. Fourth European Conference on Clinical Hemorheology. Part II. Round Table: Cerebral Ischemia and Clinical Haemorheology. Clinical Hemorheology 6:17-33, 1986.
• Hsu CY, Faught RE Jr, Furlan AJ, Coull BM, Huang DC, Hogan EL, Linet OI, Yatsu FM. Intravenous prostacyclin in acute non-hemorrhagic stroke: A placebo controlled double blind trial. The Prostacyclin Study Group. Stroke 18:352-358, 1987.
• Coull BM, Bourdette DN, Briley DP, Goodnight SH and Hart R. Multiple cerebral infarctions and dementia associated with anticardiolipin antibodies. Stroke 18:1107-1112, 1987.
• Woodward WR, Coull BM. Effects of kainic acid lesions in lateral geniculate nucleus: Activity-dependence of retrograde axonal transport of fluorescent dyes. Brain Research 454:106-115, 1988.
• Tan Y, Coull BM, Knox RJ, Beamer NB, Seaman GVF, Mela-Riker L and Nordt FJ. Red blood cell fragility in acute cerebral ischemia: Effects of calcium ions and flunarizine. Clinical Hemorheology 9:273-279, 1989.
• Briley DP, Coull BM, Goodnight SH. Neurological disease associated with anticardiolipin antibodies. Annals of Neurology 25:221-227, 1989.
• Mao C, Coull BM, Golper LC, Rau MT. Anterior operculum syndrome. Neurology 39:1169-1172, 1989.
• Woodward WR, Meshul CK, Coull BM. Ultrastructural and functional evidence for the survival of corticogeniculate neurons in kainic acid lesioned lateral geniculate nucleus. Brain Research 494:42-54, 1989.
• Malinow MR, Kang SS, Taylor LM, Wong PWK, Coull BM, Inahara T, Mukerjee D, Sexton G and Upson B. Prevalence of hyperhomocyst(e)anemia in patients with peripheral arterial occlusive disease. Circulation, 79:1180-1188, 1989.
• Woodward WR, Chiaia N, Tyler TJ, Leong L and Coull BM. Organization of cortical afferent and efferent pathways in the white matter of the rat visual system. Neuroscience 36:393-401, 1990.
• Coull BM and Goodnight SH. Antiphospholipid antibodies, prethrombotic states, and stroke. Current Concepts of Cerebrovascular Disease and Stroke 25:13-18, 1990.
• Nordt FJ, Seaman GVFS, Coull BM, and Beamer NB. Hemorheological profiles of diabetic stroke patients and diabetic individuals at high risk for stroke. Clinical Hemorheology
• Nordt FJ, Jack W, and Coull BM. Influence of Naftidrofuryl, a serotonergic antagonist on erythrocyte aggregation. J. Cardiovasc. Pharm 16 (Suppl 3):529-532,1990.
• Coull BM, Malinow MR, Beamer N, Sexton G, Nordt F, and de Garmo P. Elevated plasma homocyst(e)ine: a possible independent risk factor for stroke. Stroke 21:572-576, 1990.
• Coull BM, Brockschmidt JK, Howard G, Becker C, Yatsu FM, Toole JF, McLeroy KR, and Feibel J. Stroke diagnosis and its relationship to demographics, risk factors and clinical status after stroke. Stroke 21:867-873, 1990.
• Howard G, Brockschmidt JK, Coull BM, Becker C, Feibel J, Walker MD, McLeroy KR, Toole JF, and Yatsu FM. Stroke Diagnosis: Factors influencing the diagnostic evaluation of patients following acute stroke. Clinical Epidemiology 44:293-301, 1991.
• Coull BM, Beamer N, de Garmo P, Sexton G, Nordt F, Knox R, Seaman GVF. Chronic blood hyperviscosity in subjects with acute stroke, transient ischemic attack, and risk for stroke. Stroke 22:162-168, 1991.
• Clark WM, Coull BM, Corliss L, Beamer N, Austin T, de Garmo P, Briley DP. Role of leucocyte adhesion in clinical stroke. Journal of Cerebrovascular Disease 2:80-84,1992.
• Coull BM, Clark WM. Abnormalities of hemostasis in ischemic stroke. Med Clin North Am 77:77-94,1993.
• Clark WM, Walsh CR, Briley DP, Coull BM. Neutrophil adhesion in central nervous system ischemia in rabbits. Brain Behavior and Immunity 7:63-69,1993.
• Clark WM, Coull BM, Briley DP, Mainolfi E, Rothlein R. Circulating intercellular adhesion molecule-1 levels and neutrophil adhesion in stroke. Journal of Neuroimmunology 44:123-126,1993.
• Beamer NB, Coull BM, Sexton G, de Garmo P, Knox R, Seaman G. Fibrinogen and the albumin/globulin ratio in recurrent stroke. Stroke 24:1133-1139,1993.
• Goodnight SH, Coull BM, McAnulty JH, Taylor LM. Recommendations for the use of antiplatelet therapy in cardiac, cerebral and peripheral vascular disease. Part I Western J Med 158:385-392,1993.
• Goodnight SH, Coull BM, McAnulty JH, Taylor LM. Recommendations for the use of antiplatelet therapy in cardiac, cerebral and peripheral vascular disease. Part II Western J Med 158:506-514,1993.
• Olson JC, Konkol RJ, Gill JC, Dobyn WB, Coull BM. Childhood stroke and lupus anticoagulant. Pediatric Neurology 10:54-57,1993.
• Clark W, Hotan T, Lauten J, Coull BM. Therapeutic efficacy of tirilazad in experimental multiple cerebral emboli. Critical Care Med. 22,1161-1166,1994.
• Clark WM, Calcagno FA, Gabler WL, Smith JR, Coull BM. Reduction of central nervous system reperfusion injury in rabbits using doxycycline treatment. Stroke 25:1411-1416,1994.
• Briley DP, Giraud GD. Beamer NB, Spear EM, Grauer SE, Edwards JM, Clark WM, Sexton GJ, Coull BM. Spontaneous echo contrast and hemorheologic abnormalities in cerebral vascular disease. Stroke 25:1564-1569,1994.
• Barnwell SL, Clark WM, Nguyen TT, O'Neil OR, Wynn ML, Coull BM. Safety and efficacy of delayed intra arterial urokinase therapy with mechanical clot disruption for thromboembolic stroke. AJNR 15:1817-1822,1994.
• Beamer NB, Coull BM, Clark WM, Hazel JS, Silberger JR. Interleukin 6 and interleukin 1 receptor antagonist in acute stroke. Annals of Neurology 37: 800-805, 1995
• Grotta J, Clark W, Coull B, Pettigrew C, Mackay B, Goldstein L, Meissner I, LaRue L. Safety and tolerability of the glutamate antagonist CGS19755 (Selfotel) in patients with acute ischemic stroke: results of a phase IIa randomized trial. Stroke 26:602-605, 1995.
• Clark W, Lauten J, Beamer N, Coull B. Cytokine and superoxide production in clinical stroke. J Stroke and Cerebrovascular Disease, 5:166-171,
• Clark W, Lauten J, Lessov N, Woodward W, Coull B. Time course of ICAM-1 expression and leukocyte subset infiltration. Molecular and Chem NeuroPath 26:213-230, 1995.
• Clark W, Barnwell S, Nesbitt G, O'Neill O, Wynn M, Coull B. Safety and efficacy of percutaneous transluminal angioplasty for intracranial atherosclerotic stenosis. Stroke 26:1200-1204, 1995.
• Clark W, Lauten J, Lessov N, Woodward W, Coull B. Anti-adhesion treatments modify leukocyte subset accumulation in rat forebrain ischemia. J Molecular Neuroscience 6:43-50,1995.
• Clark W, Hazel J, Coull B. Lazaroids: central nervous system pharmacology and current research. Drugs 50:971-983,1995.
• Grotta J. Clark W, Coull BM, Pettigrew LC, Mackay B, Goldstein LB, Meissner I, Murphy D, LaRue L. Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial. Stroke, 26(4):602-5, 1995.
• Press RD, Liu XY, Beamer N, Coull BM. Ischemic Stroke in the Elderly: Role of the Common Factor V Mutation Causing Resistance to Activated Protein C. Stroke 27:44-48, 1996.
• Clark W, Coull B, Hendin B, Kelly R, Rosing H, Zachariah S, Reivich M, Walsche T, Singer S. Randomized trial of cervine, a kappa receptor selective opioid antagonist, in acute ischemic stroke. J Stroke CerebroVasc Dis 6:35-39, 1996.
• Beamer N, Giraud G, Clark W, Wynn M, Coull B. Diabetes, hypertension and erythrocyte aggregation in acute stroke. J Stroke CerebroVasc Dis 7:144-149, 1997.
• Mohr JP, Albers GW, Amarenco P, Babikian VL, Biller J, Brey RL, Coull BM, Easton JD, Gomez CR, Helgason CM, Case CS, Pullicino PM, Turpie AG. American Heart Association Prevention Conference, IV. Prevention and Rehabilitation of Stroke. Etiology of Stroke. (Meeting Report) Stroke 28:1501-6, 1997.
• Clark WM, Beamer NB, Wynn M, Coull BM. The initial acute phase response predicts long-term stroke recovery. J Stroke CerebroVasc Dis 7:128-131, 1998.
• Beamer NB, Coull BM, Clark WM, Briley DP, Wynn M, Sexton G. Persistent inflammatory response in stroke survivors. Neurology 50:1722-1728, 1998.
• Kowdley KV. Coull BM. Orwoll ES. Cognitive impairment and intracranial calcification in chronic hypoparathyroidism. American Journal of the Medical Sciences. 317:273-7, 1999.
• Press RD, Beamer NB, Evans A, Coull BM, DeLoughrey TG. A common mutation in the homocysteine regulatory enzyme methylenetetrahydrofolate reductase (MTHFR) in ischemic stroke. Diagnos Molec Pathol 8:54-58, 1999.
• Beamer NB, Coull BM, Clark WM, Wynn M. Microalbuminuria in ischemic stroke. Arch Neurol 56:699-702,
• Secomb TW, Hsu R, Beamer NB, Coull BM. “Theoretical simulation of oxygen transport to brain by networds of microvessels: Effects of oxygen supply and demand on tissue hypoxia.” Microcirculation 2000; 7:237-247.
• Ritter LS, Orozco JA, Coull BM, McDonagh PF. Leukocyte accumulation and hemodynamic changes in the cerebral microcirculation during early reperfusion after stroke. Stroke 2000; 31: 1153-1161.
• Fridriksson J, Holland AL, Coull B, Plante E, Trouard T, Plante E. Aphasia severity: Association with cerebral perfusion and diffusion. Aphasiology (in press).
• Coull BM, Williams LS, Goldstein LB et al. Anticoagulants and antiplatelet agents in acute ischemic stroke: Report of the Joint Stroke Guideline Development Committee of the American Academy of Neurology and the American Stroke Association (a division of the American Heart Association). Stroke 2002; 33:1934-1942.
• Funk JL, Migliati E, Chen G, Wei H, Coull B, et al. Parathyroid hormone-related protein induction in focal stroke: A neuroprotective vascular peptide. Am J Physiol 2002.
• Austin H, Chimowitz MI, Hill H, Coull B, et al. Cryptogenic stroke in relation to genetic variation in clotting factors and other genetic polymorphisms among young men and women. Stroke 2002; 33:2762-2769.
• Coull, Bruce M. Statin therapy after acute ischemic stroke in the Heart Protection Study: Is the role in recurrent stroke prevention now defined? Stroke 2004; 35(9):2233-2234. .

Chapters, Books, and Miscellaneous Reviews:

• Cutler RWP and Coull BM. Amino acid transport in the brain. In: Taurine and Neurological Disorders (Barbeau A and Huxstable RJ, eds). Raven Press, New York, NY, pp 95-107, 1978.
• Yatsu FM and Coull BM. Acute medical therapy of ischemic strokes and the role of prostaglandins. In: Advances in Stroke Therapy (Rose RC, ed). Raven Press, New York, NY, pp 95-107, 1982.
• Coull BM. Cerebrovascular disease. In: Geriatric Medicine: Principles and Practice, (Cassel C and Walsh J, eds). Springer-Verlag, New York, NY, pp 25-35, 1984.
• Coull BM. Neurologic aspects of dementia. In: Geriatric Medicine: Principles and Practice, (Cassel C and Walsh J, eds). Springer-Verlag, New York, NY, pp 36-49, 1984.
• Coull BM, Shah AB, Beamer NB and Miller VT. Enhanced in vivo platelet activation and subtypes of ischemic stroke. In: Cerebrovascular Diseases, (Plum F and Pulsinelli W, eds). Raven Press, New York, NY, pp 229-235, 1985.
• Miller VT, Coull BM, Yatsu FM, Shah AB and Beamer NB. Prostacyclin therapy for acute stroke. In: Cerebrovascular Diseases, (Plum F and Pulsinelli W, eds). Raven Press, New York, NY, pp 235-239, 1985.
• Binder LM, Howieson D and Coull BM. Stroke: Causes, consequences and treatment. In: Rehabilitation Psychology Desk Reference, (Caplan B, ed). Aspen Publishing Company, Rockville, MD, pp 65-100, 1987.
• Yatsu FM and Coull BM. Barbiturates therapy of ischemic strokes. In: Medical Therapy of Acute Stroke, (Fisher M, ed). Marcel Dekker, Inc., New York, NY, pp 109-114, 1989.
• Coull BM, Mela-Riker L and Tan Y. Calcium channel blockers in stroke. In: Medical Therapy of Acute Stroke, (Fisher M, ed). Marcel Dekker, Inc., New York, NY, pp. 143-163,
• Coull BM, Nordt F, Beamer NB and Seaman GVF. Hemorheological abnormalities as physicochemical risk factors for cerebral infarction. In: Cerebral Ischemia and Hemorheology, (Hartmann A and Kuschinsky W, eds). Springer-Verlag, Berlin-Heidelberg, pp. 520-527, 1987.
• Makler MT, Piper RC and Coull BM. Erythrocyte membrane changes associated with ligands which bind to the glycophorins. In: Red Blood Cells as Carriers for Drugs; Potential Therapeutic Applications: Advances in Biotechnology, Volume Pergamon Press, pp 251-260, 1987.
• Seaman GVF, Beamer NB, Coull BM, deGarmo P, Knox RJ, and Nordt FJ. Relationship between bulk flow properties of blood and carotid artery changes in cerebrovascular disease. In: International Symposium on Biofluid Mechanics, Blood Flow in Large Arteries: Applications to Atherogenesis and Clinical Medicine, (Leipsh D, ed). Proceeding Production, The Brown Agency, Rancho Mirage, CA, 1988.
• Beamer NB, Coull BM, Illingworth DR, Hagemenas FC, Nordt FJ, Knox RJ, deGarmo P,and Seaman GVF. Effect of lipid lowering therapy on blood viscosity in familial hyperlipidemia. : 16th Princeton Conference on Cerebral Vascular Diseases, (Ginsberg M and Dietrich WD, eds). Raven Press, New York, NY, pp. 281-287, 1989.
• Coull BM. Stroke in the young patient - coagulation disturbances. In: Stroke: Clinical Updates, Volume National Stroke Association, Englewood, CO, pp. 9-12, 1990.
• Coull BM, Levine SR, Brey RC. The role of Antiphospholipid Antibodies in Stroke. Cerebral Ischemia: Treatment and Prevention (HJM Barnett, ed) Neurologic Clinics 10:125-143,1992.
• Coull BM, Briley DP. "Rehabilitation and Outcome of Ischemic Stroke" in:
• Cerebrovascular Occlusive Disease and Brain Ischemia. (Awad, AA, ed.) Neurosurgical Topics The American Association of Neurological Surgeons pp. 265-280,1992.
• Coull BM, Goodnight SH. Antiphospholipid Antibodies and Coagulation Disorders in Ischemic Stroke. In STROKE: Pathophysiology, Diagnosis, and Management, second edition. (Henry J.M. Barnett, J.P. Mohr, Bennett M. Stein, Frank M. Yatsu, editors). Churchill Livingstone Inc. New York, NY, pp 859-873,1992.
• Coull BM, Goodnight SH. Hematological abnormalities in stroke. In Handbook of Cerebrovascular Diseases, (Harold P. Adams,Jr., Editor). Marcel Dekker, Inc. New York, NY,pp 191-220,1993.
• Clark WM, Coull BM, Beamer NB. Need for treatment of elevated plasma fibrinogen in cerebrovascular disease. Heart Disease and Stroke 2:503-506,1993.
• Coull BM, Beamer NB, Clark WM, Howard G. Acute Phase Response in Atherothrombotic Stroke In: Cerebrovascular Diseases, Nineteenth Princeton Stroke Conference (Moskowitz MA and Caplan LR, eds).Butterworth-Heinemann, Boston MA, pp. 111-122, 1995.
• Wynn ML, Coull BM. Evaluation of ischemic stroke and recurrent ischemic attack. Laboratory Medicine 26:519-523, 1995.
• Coull, BM. The many windows of therapeutic opportunities in stroke. Current Opinion in Neurology 9:43-45, 1996
• Brey RL, Coull BM. Cerebral venous thrombosis. Role of activated protein C resistance and factor V gene mutation (editorial; comment). Stroke 27(10):1719-20, 1996.
• Oddone E, Booss J, Brass LM, Coull B, Goldstein L, Gorelick P, Horner R, Matchar D, Provenzale J, Kaplan L. Acute stroke management in the VA: A toolbox to assist patient care. Federal Practitioner, (in press).
• Levine SR, Coull BM. Potassium depletion as a risk factor for stroke. Will a banana a day keep your stroke away? (editorial) Neurology, 59:302-303, 2002.
• Coull, BM, Brey R. Coagulation abnormalities in stroke. In: Stroke – Pathophysiology, Diagnosis, and Management, 4^th Ed, (Mohr JP, Choi DW, Grotta JC, Weir B, Wolf PA, Eds). Churchill Livingstone:New York, NY 707-724, 2004.

Abstracts and Letters:

• Intermittent photic stimulation: Clinical usefulness of non-convulsive response. American EEG Society. Miami, Florida, June 1977.
• Light evoked release of glycine into the vitreous of the intact rat eye. Transactions of the American Society of Neurochemistry Abstracts 9:100, 1978.
• Phipps T, Coull BM, Duvall ER and Howieson J. Correlation of CT findings with magnitude of stroke deficit. North Pacific Society of Neurology and Psychiatry. Bend, Oregon. March 26, 1980.
• Cawthor ML, Coull BM and Smith WB. Significance of increased serum alkaline phosphatase in epileptics. North Pacific Society of Neurology and Psychiatry. Bend, Oregon. March 27, 1980.
• Yatsu FM, Coull BM, Osterud HT and Kennedy JH. Impact on stroke care in a mixed urban/rural population: use of "stroke teams." Crisis in the Public Sector: Challenge to the Public Health, Program and Abstracts: 140, 1980.
• Woodward WR and Coull BM. Kainic acid neurotoxicity in the rat lateral geniculate nucleus. Society of Neuroscience Abstracts 6:838, 1980.
• Coull BM and Woodward WR. Evidence against acetylcholine as a neurotransmitter of rat geniculocortical neurons. American Society of Neurochemistry Abstracts 12:244, 1981.
• Connor WR, Rapp J, Lin D and Coull BM. The source of cholesterol ester in human atherosclerosis: Plasma vs. Local synthesis. American Federation of Clinical Research. San Francisco, CA. April 24-26, 1981.
• Yatsu FM, Coull BM, Toole JF, McElroy K, Feibel JH, Springer CA and Walker MD. Regional stroke survey: Demography and outcome. Stroke 13:124, 1982.
• Miller VT, Coull BM, Seaman GVF and Jackson L. Anti-aggregate effects of ibuprofen: A potential alternative treatment of TIAs in aspirin-intolerant patients. Neurology 32:A-197, 1982.
• Howard G, Toole JF, Becker C, McElroy K, Feibel J, Springer C, Yatsu FM, Coull BM and Walker MD. Survivorship of strokes: Regional stroke survey. Neurology 32:A-187, 1982.
• Hart RG, Coull BM, Miller VT and Yatsu FM. Evaluation of cerebral infarction in young adults. Neurology 32:A-198, 1982.
• Woodward WR, Coull BM and Kaplan M. Segregation of corticofugal and geniculocortical Science 22:244, 1982.
• Coull BM, Woodward WR and Weleber RG. Effect of kainic acid lesions in the lateral geniculate nucleus on the corticofugal pathways of the rat visual system. Investigative Ophthalmology and Visual Science 22:244, 1982.
• Hart RG, Miller VT and Coull BM. Rebound hypercoagulability. (Letter) Stroke 13:527,
• Hart RG, Miller VT and Coull BM. Medical management of subarachnoid hemorrhage. (Letter) Stroke 13:722-723, 1982.
• Hart RG, Coull BM and Miller VT. (Letter) Neurology, 1982.
• Woodward WR and Coull BM. Is retrograde axonal transport of fluorescent dyes dependent on impulse activity in neurons? Society of Neuroscience Abstracts 8:789, 1982.
• Hart RG and Coull BM. Practical considerations in antifibrinolytic therapy. Stroke 13:5, 1982.
• Shah AB, Coull BM, Howieson J, Ono H, Nutt JG, Blank NK and Carter J. Does the natural history of transient ischemic attacks (TIA) justify surgery? (Letter) Stroke 14:827-828, 1983
• Hart RG and Coull BM: Hypercoagulability following Coumadin withdrawal (Letter) Stroke 14:133, 1983.
• Toole JF, Feibel J, Yatsu FM, Becker C and Coull BM. Comprehensive Stroke Center Data Base in North Carolina, Oregon and Monroe County, New York. Annals of Neurology 14:133, 1983.
• Shah AB, Coull BM and Beamer NB. In vivo platelet activation and strokes in young adults with migraine. Neurology 33 [Suppl 2]:206, 1983.
• Woodward WR and Coull BM. Organization of geniculocortical and corticofugal fiber tracts within the subcortical white matter. Investigative Ophthalmology and Visual Science 24:64, 1983.
• Coull BM and Woodward WR. Dependence of retrograde fluorescent dye transport on impulse activity in corticogeniculate neurons. Investigative Ophthalmology and Visual Science 24:226, 1983.
• Woodward WR and Coull BM. Course and structural organization of geniculocortical and corticofugal pathways in white matter of the rat visual system. Society Neuroscience Abs. 9:35, 1983.
• Shah AB, Coull BM and Beamer NB. Differences in platelet activation in subtypes of ischemic stroke. Stroke 15:184, 1984.
• Shah AB, Blank NK and Coull BM. Controversy of heparin therapy in stroke in evolution" (SIE): Need for a well designed study. Neurology 34, Supplement 1:284, 1984.
• Shah AB, Coull BM, Beamer NB, Miller VT and Howieson J. Platelet activation in stroke: Evidence supporting a causal role of platelets in subtypes of ischemic stroke. Neurology 34 [Suppl 1]:203, 1984.
• Shah AB, Coull BM and Beamer NB. Failure of aspirin to prevent in vivo platelet activation in acute stroke. Annals of Neurology 16:154, 1984.
• Lezak MD, Coull BM and Wiens AN. Neuropsychological deficit patterns associated with exposure to airborne toxic substances. 13th Annual Meeting of the International Neuropsychological Society, San Diego, California, February 1985.
• Coull BM, Beamer NB, Seaman GVF and Nordt FJ. Contributions of hemorheological factors to stroke. Clinical Hemorheology 5:666, 1985.
• Seaman GVF and Coull BM. Physiochemical risk factors in stroke. Clinical Hemorheology 5:711, 1985.
• Coull BM, Beamer NB and Seaman GVF. The contribution of hemorheologic factors to cardioembolic stroke. Journal of Neurology 232:197, 1985.
• Coull B, Bourdette D, Goodnight Jr S, Gill T, Hart R. Multiple cerebral infarctions associated with antibodies to cardiolipins. Neurology 36[Suppl 1]:252, 1986.
• Woodward WR, Gumerlock MK, Walker CM, Leong L, Gill TH and Coull BM. Morphometric changes in cortical neurons following ischemia. Society of Neuroscience Abstracts 12:64, 1986.
• Meshul CK, Woodward WR, Walker CM and Coull BM. Survival of axon terminals in a kainic acid lesion site: A retrograde transport and electron microscopic study. Society of Neuroscience Abstracts 12:96, 1986.
• Coull BM, Beamer NB, Seaman GVF and Illingworth RD. Hemorheological profile in patients with familial hypercholesterolemia: Effect of lipid lowering therapy. Abstracts of the 5th European Conference. Clinical Hemorheology 7:468, 1987.
• Tan Y, Coull BM, Nordt FJ, Knox RJ, Beamer NB and Seaman GVF. Red blood cell fragility in cerebral ischemia: Influence of flunarizine. Abstracts of the 5th European Conference. Clinical Hemorheology 7:467,
• Briley DP, Coull BM and Goodnight Jr SH. Neurological disease associated with anticardiolipin antibodies. Annals of Neurology 22:136, 1987.
• deGarmo PL, Coull BM, Sexton G, Beamer NB, Knox RJ, Seaman GVF and Nordt FJ. Whole blood viscosity as a measure for degree of risk in stroke. Neurology 38:296, 1988.
• Gumerlock MK, Walker CM, Woodward WRW, Coull BM. Kainic acid protection against post-ischemic seizures. Stroke 19:142, 1988.
• Coull BM. Solicited Editorial response to "Stroke in an intravenous drug user secondary to lupus anticoagulant" by Taber KA and Anderson B. Stroke 19:274-275, 1988 (letter with editorial reply by Coull BM).
• Knox RJ, Beamer NB, Coull BM, Nordt FJ, deGarmo PL and Seaman GVF. Red blood cell sialic acid and blood viscosity in heart valve patients. Blood 7(5) Supplement 1:29A, 1988.
• Coull BM, Beamer NB, Knox R, deGarmo P, Nordt FJ and Seaman GVF. Plasma components of elevated whole blood viscosity in acute stroke. Stroke 20:136, 1989.
• Coull BM, Malinow MR and Beamer N. Elevated plasma homocysteine in acute stroke: relationship to risk factors. Neurology 39 [Suppl]:303, 1989.
• Coull BM, Sexton G, Beamer N, and Nordt F. Physiologic, Pharmacologic, and Epidemiologic Variables which distinguish subjects with acute stroke from those at risk. Neurology 40 [Suppl]: 324, 1990.
• Nordt FJ, Coull BM, Beamer NB, deGarmo PL, Stevry A: Controlled study of rheological factors in subjects with acute cerebral infarction, TIA and at-high-risk for stroke. Abstracts: First World Congress of Biomechanics 2:277. La Jolla, CA 1990.
• Coull BM, Beamer NB, deGarmo PL, Sexton GJ, Nordt FJ: Plasma proteins, diabetes mellitus, and recurrent stroke. Stroke 22: Jan 1991.
• Briley DP, Coull BM. Antiphospholipid antibodies and vascular dementia. Neurology 41 (Suppl 1):296,1991.
• Coull BM, Briley DP, Beamer NB, Clark WM. Stroke recurrence, stroke mechanism, and diabetes mellitus. Neurology 42 (Suppl 3):272,1992.
• Clark WM, Coull BM, Briley DP, Walsh CR. Neutrophil adhesion in experimental central nervous system ischemia. Stroke 42 (Suppl 3):361,1992.
• Clark WM, Briley DP, Coull BM. Leucocyte adhesion in clinical stroke. Stroke 23:152, 1992.
• Briley DP, Giraud G, Spear G, Coull BM, Edwards J, Clark WM. Spontaneous echo contrast, ischemic stroke, and risk of recurrent stroke. Annals of Neurology 32:237, 1992.
• Coull BM, de Garmo PL, Beamer NB, Briley DP, Clark Wm. Application of the Framingham Stroke Risk Profile to stroke recurrence: the Oregon Stroke Center Database. Annals of Neurology 32:265-266,1992.
• Spear EM, Briley DP, Grauer SE, Edwards JM, Clark WM, Coull BM, Giraud GD. Spontaneous echo contrast, fibrinogen and plasma viscosity in stroke patients. Circulation, 1992.
• Coull BM, Beamer NB, Clark WM. Elevated plasma interleukin-6 in acute stroke. Stroke 24:183,1993.
• Briley DP, Coull BM, Beamer NB, de Garmo PL, Clark WM. Relationship between carotid stenosis and elevated fibrinogen in stroke. Stroke 24:186,1993.
• Clark WM, Barnwell SL, Coull BM. Safety and efficacy of delayed intra-arterial urokinase therapy for thromboembolic stroke. Stroke 24:190,1993.
• Clark WM, Hotan T, Lauten J, Coull BM. Tirilazad improves neurologic recovery and reduces neutrophil adhesion in experimental stroke. Neurology 43 (Suppl 2):A366,1993.
• Coull BM, Austin T, Beamer N, Clark WM. Relationship between the NIH stroke scale , the Mini-Mental Status Exam, and functional stroke outcome. Neurology 43 (Suppl 2):A244, 1993.
• Clark W, Lauten J, Coull B, Cherry N, Woodward W. ICAM-1 and IL-6 changes in the hippocampus following transient forebrain ischemia in the rat. Soc Neurosci. (in press).
• Hazel S, Coull BM, Beamer N, Clark WM, McCall AL. Fibrinogen and poor early outcome after ischemic stroke. Stroke 25:246, 1994.
• Coull BM, Briley DP, Clark WM, Beamer N, Giraud G. Spontaneous echo contrast (SEC) in ischemic stroke: the role of cardiac and hemorheologic abnormalities. Stroke 25:258, 1994.
• Clark WM, Lauten JD, Woodward WW, Coull BM. Delayed ICAM-1 expression and macrophage infiltration on rat forebrain ischemia. Stroke 25:266, 1994.
• Clark WM, Calcagno FA, Smith J, Gabler WL, Coull BM. Therapeutic efficacy of doxycycline in experimental CNS reperfusion injury. Stroke 25:266, 1994.
• Clark WM, Barnwell SL, Young LM, Coull BM. Safety and efficacy of angioplasty for intracranial atherosclerotic stenosis. Stroke 25: 273, 1994.
• Wynn M, Clark W, Radakovich E, Coull B. Risk of cerebrovascular events in cardiac transplant patients. Neurology 44(Suppl 2): A128, 1994.
• Lauten JD, Clark WM, Woodward WR, Coull BM. Time course of ICAM- expression and leukocyte subset infiltration in rat forebrain ischemia. Neurology 44(Suppl 2): A191, 1994.
• Clark WM, Coull BM, for the CGS 19755 Study Group. Randomized trial of CGS 19755, a glutamate antagonist, in acute ischemic stroke treatment. Neurology 44(Suppl 2): A270, 1994.
• Coull BM, Beamer N, Clark W. Elevated fibrinogen and plasma interleukin-6 (IL-6) in acute stroke. Neurology 44(Suppl 2): A289, 1994.
• Clark WM, Calcagno FA, Smith JR, Gabler WL, Coull BM. Doxycycline improves neurologic recovery and reduces leukocyte adhesion in experimental central nervous system ischemia. Neurology 44(Suppl 2): A341, 1994.
• Clark W, Barnwell S, O'Neill O, Ahuja A, Wynn M, Coull B. Successful middle cerebral artery thrombolysis by microcatheter navigation through an occluded internal carotid artery. Stroke 26:167, 1995.
• Coull BM, Beamer N, Clark W, Ramsay C, Hazel S. Enhanced erythrocyte aggregation in acute stroke. Stroke 26:162, 1995.
• Clark WM, Lauten J, Lessov N, Woodward W, Coull B. Anti-adhesion treatments modify leukocyte subset accumulation in rat forebrain ischemia. Stroke 26:169,1995.
• Clark WM, Lauten J, Hazel K, Lessov N, Coull B. Doxycycline improves functional outcome after transient middle cerebral artery occlusion in the rat. Neurology 45(suppl 4): A311,1995.
• Clark WM, Coull B, Hendin B, Kelly R, Rosing H, Zachariah S, Winograd M, Reivich M, Walshe T. Randomized trial of cervine, a kappa receptor selective opioid antagonist, in acute ischemic stroke. Neurology 45(Suppl 4): A241,1995.
• Clark WM, Lauten JD, Lessov N, Hazel K, Coull BM. Inhibition of leukocyte adhesion in experimental CNS ischemia. Biorheology 32: 162-169, 1995.
• Beamer N, Giraud G, Wynn M, Clark WM, Nygard C, Coull BM. Glycosylated hemoglobin and RBC aggregation in stroke. Biorheology 32:163-169, 1995.
• Coull BM, Beamer N, Anderson G, Clark WM, Ramsay C, Giraud G, Hazel S. Erythrocyte aggregation in subtypes of ischemic stroke. Biorheology 32:163-169, 1995.
• Giraud GD, Grauer SE, Beamer NB, Clark WM, Coull BM. The relationship between spontaneous echo contrast and hemorheologic abnormalities in patients with cerebrovascular disease. Biorheology 32: 163-169,
• Coull BM, Beamer N, McAnulty J, Giraud G, Clark WM. Clinical and Rheological Risk for Thromboembolism in Atrial Fibrillation. Stroke 27: 166, 1996.
• Clark WM, Hazel S, Beamer N, Wynn M, Coull BM. The Initial Acute Phase Response Predicts Long Term Stroke Recovery. Stroke 27: 186, 1996.
• Coull BM, Beamer N, Clark W, Wynn M. Angiotensin-Converting Enzyme Inhibitors Reduce Risk of Recurrent Stroke, Myocardial Infarction and Vascular Death. Neurology 46: 424, 1996.
• Press RD, Beamer N, Coull B. A common mutation in methylenetetrahydrofolate reductase in stroke. Stroke 28: 265, 1997.
• Coull B, Beamer N, Clark W, Wynn M. Influence of cerebro- and cardiovascular risk factors on recurrent stroke. Stroke 28: 238, 1997.
• Coull B, Beamer N, Clark W, Wynn M. Persistently elevated fibrinogen after atheroembolic stroke. Neurology 48(2):A372. 1997.
• Coull BM, Beamer NB, Clark WM, Wynn M. Microalbuminuria and the risk of recurrent stroke. Stroke 29: 285,1998.
• Ritter LS, Coull BM, Davis-Forman G, McDonagh PF. Early in reperfusion following stroke, leurocytes rapidly accumulate in the cerebral microcirculation. Stroke 29: 329, 1998.
• Feldman LA, Wynn M, Coull BM, McAnulty JH,Giraud GD. The relationship between left atrial spontaneous echocardiographic contrast and cerebral microemboli in patients with atrial fibrillation. Circulation 96(8):1-104, 1997.
• Coull BM, Beamer NB. Serum potassium levels in ischemic stroke. Neurology 52(2):A105-A106, 1999.
• Beamer NB, Coull BM. Vitamin use in patients with ischemic stroke. Neurology 52(6) Suppl 2:A64, 1999.
• Leslie S. Ritter, Bruce M. Coull, Paul F. McDonagh, "Middle cerebral artery occlusion and reperfusion results in significant leukocyte accumulation in the microcirculation."The FASEB Journal, 13(5): 13.29, March 15, 1999.
• L. Ritter, B. Coull, P. McDonagh, and J. McDonagh. "Reduced shear rate is associated with significant leukocyte accumulation in the cerebral microcirculation after middle cerebral artery occlusion and reperfusion." Soc. Neuroscience Abstr, 25:1033, 1999.
• Secomb, TW, Hsu R, Beamer NB, Coull BM: Effects of blood perfusion and oxygen consumption of brain tissue: Theoretical simulation of oxygen transport by networks of microvessels. Stroke 31:341, 2000.
• L. Ritter, J. Orozco, B. Coull, and P. McDonagh. An increase in leukocyte rolling in venules is observed during early leukocyte reperfusion after stroke. The FASEB Journal, 14(4), A13, 2000.
• Fridriksson J, Holland AL, Coull BM, Plante E, Beeson P, Trouard T. Association between cerebral perfusion/diffusion and aphasia severity in stroke. Stroke 33(1):366, 2002.
• Levine SR, Coull BM,. Potassium depletion as a risk factor for stroke: Will a banana a day keep your stroke away? Neurology 2002; 59(3):302-303.
• Olson SE, Erly WK, Coull BM. Stroke etiology affects DWI lesion pattern in single territory ischemic strokes. Neurology 2003; 60 (Suppl 1): A309.